Lubiprostone Effects on Visceral Pain Sensitivity
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| Description | Clinical trials of Lubiprostone have shown that this medication decreases clinical pain associated with IBS. This study is to determine how this medication works to decrease pain. It is predicted that it works by decreasing pain sensitivity. |
| Contact | Jane Tucker, RN (919) 843-4906 (email) |
| Phone | 919-966-0289 |
| Requirements | This is an 8 week study that requires taking Lubiprostone or a placebo for 4 weeks each. This will involve 7 visits to UNC. To be eligible, male or female subjects must be age 18 or older and diagnosed with constipation predominant IBS. You should not participate if you are using IBS specific drugs or medications likely to cause constipation, or you are pregnant or planning to become pregnant. |
| Compensation | Subjects will be paid up to $500 for completing this study. If interested, subjects may also choose to participate in another add-on study with additional compensation. |