Seminar: David Fruman, PhD (UC Irvine)
1131 Bioinformatics 130 Mason Farm Road, Chapel Hill, NC, United StatesDAVID FRUMAN, PHD ǀ University of California- Irvine Host: Pengda Liu “Strategies to target the mTORC1/eIF4F Axis in B-cell malignancies” Abstract: mTOR complex-1 (mTORC1) is a key regulator of B cell proliferation and differentiation. Elevated mTORC1 activity is also common in B cell cancers and is associated with poor prognosis. We have shown that … Read more