Klaus Hahn, PhD, is the Ronald Thurman Distinguished Professor at University of North Carolina at Chapel Hill. His lab develops small molecules and proteins to visualize and control signaling in living cells. These tools enable us to ask how the spatio-temporal dynamics of protein activity govern signaling. The Hahn Lab is developing means to control endogenous proteins with light, and engineering allosteric networks in proteins to confer control by light or small molecules. In metastatic cells they are examining coordination of Rho family GTPases and their upstream regulators, asking why each GTPases is regulated by multiple GEFs, GDIs, and GAPs, and how space and time play a role in this complex circuitry.
Zoom passcode: Seminar