Publications

Liu C, Mokashi NV, Darville T, Sun X, O’Connell CM, Hufnagel K, Waterboer T, Zheng X. A Machine Learning-Based Analytic Pipeline Applied to Clinical and Serum IgG Immunoproteome Data To Predict Chlamydia trachomatis Genital Tract Ascension and Incident Infection in Women. Microbiol Spectr. 2023 Aug 17;11(4):e0468922. doi: 10.1128/spectrum.04689-22. Epub 2023 Jun 15. PMID: 37318345.

Zhong W, Kollipara A, Liu Y, Wang Y, O’Connell CM, Poston TB, Yount K, Wiesenfeld HC, Hillier SL, Li Y, Darville T, Zheng X. Genetic susceptibility loci for Chlamydia trachomatis endometrial infection influence expression of genes involved in T cell function, tryptophan metabolism and epithelial integrity. Front Immunol. 2022 Sep 29;13:1001255. doi: 10.3389/fimmu.2022.1001255. PMID: 36248887.

Huang C, Callahan BJ, Wu MC, Holloway ST, Brochu H, Lu W, Peng X, Tzeng JY. Phylogeny-guided microbiome OTU-specific association test (POST). Microbiome. 2022 Jun 7;10(1):86. doi: 10.1186/s40168-022-01266-3. PMID: 35668471.

Geisler WM, Hocking JS, Darville T, Batteiger BE, Brunham RC. Diagnosis and Management of Uncomplicated Chlamydia trachomatis Infections in Adolescents and Adults: Summary of Evidence Reviewed for the 2021 Centers for Disease Control and Prevention Sexually Transmitted Infections Treatment Guidelines. Clin Infect Dis. 2022 Apr 13;74(Suppl_2):S112-S126. doi: 10.1093/cid/ciac126. PMID: 35416965.

Liu C, Hufnagel K, O’Connell CM, Goonetilleke N, Mokashi N, Waterboer T, Tollison TS, Peng X, Wiesenfeld HC, Hillier SL, Zheng X, Darville T. Reduced Endometrial Ascension and Enhanced Reinfection Associated With Immunoglobulin G Antibodies to Specific Chlamydia trachomatis Proteins in Women at Risk for Chlamydia. J Infect Dis. 2022 Mar 2;225(5):846-855. doi: 10.1093/infdis/jiab496. PMID: 34610131.

Liu Y, Darville T, Zheng X, Li Q. Decomposition of variation of mixed variables by a latent mixed Gaussian copula model. Biometrics. 2022 Mar 19. doi: 10.1111/biom.13660. Epub ahead of print. PMID: 35304917.

Darville T. Pelvic Inflammatory Disease Due to Neisseria gonorrhoeae and Chlamydia trachomatis: Immune Evasion Mechanisms and Pathogenic Disease Pathways. J Infect Dis. 2021 Aug 16;224(12 Suppl 2):S39-S46. doi: 10.1093/infdis/jiab031. PMID: 34396413.

Zheng X, Zhong W, O’Connell CM, Liu Y, Haggerty CL, Geisler WM, Anyalechi GE, Kirkcaldy RD, Wiesenfeld HC, Hillier SL, Steinkampf MP, Hammond KR, Fine J, Li Y, Darville T. Host Genetic Risk Factors for Chlamydia trachomatis-Related Infertility in Women. J Infect Dis. 2021 Aug 16;224(12 Suppl 2):S64-S71. doi: 10.1093/infdis/jiab149. PMID: 34396400.

Mitchell CM, Anyalechi GE, Cohen CR, Haggerty CL, Manhart LE, Hillier SL. Etiology and Diagnosis of Pelvic Inflammatory Disease: Looking Beyond Gonorrhea and Chlamydia. J Infect Dis. 2021 Aug 16;224(12 Suppl 2):S29-S35. doi: 10.1093/infdis/jiab067. PMID: 34396407.

Hillier SL, Bernstein KT, Aral S. A Review of the Challenges and Complexities in the Diagnosis, Etiology, Epidemiology, and Pathogenesis of Pelvic Inflammatory Disease. J Infect Dis. 2021 Aug 16;224(12 Suppl 2):S23-S28. doi: 10.1093/infdis/jiab116. PMID: 34396398.

de la Maza LM, Darville T, Pal S. Chlamydia trachomatis vaccines for genital infections: where are we and how far is there to go? Expert Rev Vaccines. 2021 Apr;20(4):421-435. doi: 10.1080/14760584.2021.1899817. Epub 2021 Apr 28. PMID: 33682583.

Kallon S, Samir S, Goonetilleke N. Vaccines: Underlying Principles of Design and Testing. Clin Pharmacol Ther. 2021 Apr;109(4):987-999. doi: 10.1002/cpt.2207. Epub 2021 Mar 11. PMID: 33705574.

Zhong W, Darville T, Zheng X, Fine J, Li Y. Generalized multi-SNP mediation intersection-union test. Biometrics. 2020 Dec 14. doi: 10.1111/biom.13418. Epub ahead of print. PMID: 33316078.

Dong L, Kollipara A, Darville T, Zou F, Zheng X. Semi-CAM: A semi-supervised deconvolution method for bulk transcriptomic data with partial marker gene information. Sci Rep. 2020 Mar 25;10(1):5434. doi: 10.1038/s41598-020-62330-2. PMID: 32214192.

Zhong W, Dong L, Poston TB, Darville T, Spracklen CN, Wu D, Mohlke KL, Li Y, Li Q, Zheng X. Inferring Regulatory Networks From Mixed Observational Data Using Directed Acyclic Graphs. Front Genet. 2020 Feb 7;11:8. doi: 10.3389/fgene.2020.00008. PMID: 32127796.