Department of Genetics Publications for August 26 – Sept. 8, 2018

Department of Genetics faculty, postdocs, students and collaborators published eleven papers during Aug. 26 – Sept. 8, 2018.

Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways.

Howard DM, Adams MJ, Shirali M, Clarke TK, Marioni RE, Davies G, Coleman JRI, Alloza C, Shen X, Barbu MC, Wigmore EM, Gibson J, Hagenaars SP, Lewis CM, Ward J, Smith DJ,Sullivan PF, Haley CS, Breen G, Deary IJ, McIntosh AM.

Nat Commun. 2018 Aug 30;9(1):3578. doi: 10.1038/s41467-018-05310-5. No abstract available.

PMID: 30166530

Genetic control of alphavirus pathogenesis.

Baxter VK, Heise MT.

Mamm Genome. 2018 Aug 27. doi: 10.1007/s00335-018-9776-1. [Epub ahead of print] Review.

PMID: 30151711

Genetic Complexity of Mitral Valve Prolapse Revealed by Clinical and Genetic Evaluation of a Large Family.

Haskell GT, Jensen BC, Skrzynia C, Pulikkotil T, Tilley CR, Lu Y, Marchuk DS, Ann Samsa L,Wilhelmsen KC, Lange E, Patterson C, Evans JP, Berg JS.

J Heart Valve Dis. 2017 Sep;26(5):569-580.

PMID: 29762926

The Clinical Sequencing Evidence-Generating Research Consortium: Integrating Genomic Sequencing in Diverse and Medically Underserved Populations.

Amendola LM, Berg JS, Horowitz CR, Angelo F, Bensen JT, Biesecker BB, Biesecker LG, Cooper GM, East K, Filipski K, Fullerton SM, Gelb BD, Goddard KAB, Hailu B, Hart R, Hassmiller-Lich K, Joseph G, Kenny EE, Koenig BA, Knight S, Kwok PY, Lewis KL, McGuire AL, Norton ME, Ou J, Parsons DW, Powell BC, Risch N, Robinson M, Rini C, Scollon S, Slavotinek AM, Veenstra DL, Wasserstein MP, Wilfond BS, Hindorff LA; CSER consortium, Plon SE, Jarvik GP.

Am J Hum Genet. 2018 Sep 6;103(3):319-327. doi: 10.1016/j.ajhg.2018.08.007.

PMID: 30193136

Development of Clinical Domain Working Groups for the Clinical Genome Resource (ClinGen): lessons learned and plans for the future.

Milko LV, Funke BH, Hershberger RE, Azzariti DR, Lee K, Riggs ER, Rivera-Munoz EA, Weaver MA, Niehaus A, Currey EL, Craigen WJ, Mao R, Offit K, Steiner RD, Martin CL, Rehm HL, Watson MS, Ramos EM, Plon SE, Berg JS.

Genet Med. 2018 Sep 5. doi: 10.1038/s41436-018-0267-2. [Epub ahead of print]

PMID: 30181607

Inheritance of OCT4 predetermines fate choice in human embryonic stem cells.

Wolff SC, Kedziora KM, Dumitru R, Dungee CD, Zikry TM, Beltran AS, Haggerty RA, Cheng J, Redick MA, Purvis JE.

Mol Syst Biol. 2018 Sep 3;14(9):e8140. doi: 10.15252/msb.20178140.

PMID: 30177503

HUGIn: Hi-C Unifying Genomic Interrogator.

Martin JS, Xu Z, Reiner AP, Mohlke KL, Sullivan P, Ren B, Hu M, Li Y.

Bioinformatics. 2017 Dec 1;33(23):3793-3795. doi: 10.1093/bioinformatics/btx359.

PMID: 28582503

Host genetic regulation of immune-based and infectious diseases : Introduction to mammalian genome special issue: genetics of infectious disease.

Ferris MT, Hood DW.

Mamm Genome. 2018 Aug;29(7-8):365-366. doi: 10.1007/s00335-018-9779-y. No abstract available.

PMID: 30171339

INTACT Proteomics in <i>Xenopus</i>.

Wasson L, Amin NM, Conlon FL.

Cold Spring Harb Protoc. 2018 Aug 27. doi: 10.1101/pdb.prot098384. [Epub ahead of print]

PMID: 30150318

Targeting Root Cause by Systemic scAAV9-h<i>IDS</i> Gene Delivery: Functional Correction and Reversal of Severe MPS II in Mice.

Fu H, Zaraspe K, Murakami N, Meadows AS, Pineda RJ, McCarty DM, Muenzer J.
Mol Ther Methods Clin Dev. 2018 Sep 4;10:327-340. doi: 10.1016/j.omtm.2018.07.005. eCollection 2018 Sep 21.
PMID: 30191159

Local Inversion Heterozygosity Alters Recombination throughout the Genome.

Crown KN, Miller DE, Sekelsky J, Hawley RS.

Curr Biol. 2018 Aug 23. pii: S0960-9822(18)30903-5. doi: 10.1016/j.cub.2018.07.004. [Epub ahead of print]

PMID: 30174188