Skip to main content
brian-kelley
Brian Kelley, MD

Brian P. Kelley, MD, an internal medicine resident, Casey Gazda, MD, a fellow in cardiology, and Joseph A. Siyak, MD, assistant professor in cardiology, published “Loeffler Endocarditis as a Manifestation of Paraneoplastic Hypereosinophilia” in a recent issue of CASE, Cardiovascular Imaging Case.

Eosinophilic myocarditis (EM) represents a rare spectrum of heart disease that remains mysterious as to etiology and pathogenesis. Its presentation is variable and includes a fibrotic stage known as Loeffler endocarditis. The team describes a case of EM in a patient with paraneoplastic eosinophilia in the setting of metastatic renal cell carcinoma (RCC).

Midesophageal aortic valve long-axis (left) and four-chamber (right) views on transesophageal echocardiography showing ejection fraction of 30% and biventricular apical echodensities suggestive of Loeffler endocarditis.

“Although imaging findings associated with the disease are not uncommonly equivocal, echocardiography plays an important role in its diagnosis and management,” said Kelley.

Read the case here.