Three UNC researchers are joining forces with investigators at RTI International to devise solutions to address the opioid epidemic and related public health problems in eight counties in North Carolina’s western tip.
UNC McAllister Heart Institute member Monte Willis, MD, is a co-author of a scientific statement from the American Heart Association regarding the burden of heart disease among African Americans. Heart disease is the leading killer of all Americans, but in African Americans, heart disease develops earlier, and deaths from heart disease are higher than in Caucasian Americans.
Publishing their work in Nature, UNC School of Medicine researchers with the UNC McAllister Heart Institute show how their new research platform helped them discover new cell subpopulations and crucial cellular players in the process of turning damaged heart tissue back into healthy heart muscle. The research platform could be used to study other biological processes and create tailored therapies.
Brian Jensen, MD, associate professor of medicine and pharmacology, and colleagues identified for the first-time mechanisms underlying the cardiotoxicity of kinase inhibitors used to treat cancer.
Both basic and clinical studies suggest that reproductive steroids regulate virtually every element of neural signaling and do so in a highly context dependent fashion, with contexts including cell type, metabolic profiles, developmental stage/age, sex, environment, past experience, and genotype. Reproductive endocrine-related mood disorders in women (premenstrual dysphoric disorder, perinatal depression, and perimenopausal depression) offer … Read more
An elimination diet resulted in 40% of eosinophilic esophagitis patients achieving a histologic response, which was maintained in 20% after two years of treatment.
Calculating the risk of heart failure, cardiogenic shock, and death at the time of an angioplasty procedure can be critically important because early initiation of blood pressure support can improve survival.
Speaker: Ming Cui Gong, PhD, MD Professor of Physiology and Cardiovascular Research Center, University of Kentucky College of MedicineTopic: Disrupted Circadian Rhythms of Blood Pressure and Vascular Function in Diabetes
Speaker: Szymon Wiernek, MD, PhD, Fellow, UNC CardiologyTopic: Coronary Artery Disease in Patients with End-stage Renal Disease
Severe acute viral infections are one of the world’s most common causes of hospitalization and mortality with worse outcomes disproportionately affecting resource-constrained countries. In the past 15 years we have witnessed the emergence or re-emergence of several viral pathogens that threaten global public health including SARS, pandemic H1N1 Influenza, MERS-CoV, and most recently Ebola. Fischer, … Read more
Speaker: Timothy Haystead, PhD, Professor of Pharmacology and Cancer Biology, Duke University School of MedicineTopic: Defining Novel Therapeutic Targets for Cardiovascular Disease through Chemical Biology
In May, a faulty heart valve nearly put an end to Jim Weber. But after receiving a transcatheter aortic valve replacement at UNC Medical Center, Weber says he feels like he’s been gifted with years he didn’t have before. A lifelong Notre Dame fan, Weber joined Matt Cavender, the doctor who performed the valve replacement, as the Fighting Irish faced the Tar Heels at Kenan Stadium.