Research News

Patients with acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) have historically poor outcomes with conventional chemotherapy regimens. Davis Phillips, MD, internal medicine resident, and Josh Zeidner, MD, associate professor of medicine in the division of hematology, published an article that reviews the data for existing therapeutic options for patients with AML-MRC and the emerging therapies undergoing … Read more

Myron Cohen, MD, is the lead investigator of a study recently published in the Journal of the American Medical Association (JAMA) that shows bamlanivimab monotherapy reduced the incidence of infection in skilled nursing homes and assisted living facilities with high risk of SARS-CoV-2 exposure. The randomized phase 3 clinical trial included 966 residents and staff … Read more

Results of the five-year GRADE trial, designed to understand the best second-line agent for patients with type 2 diabetes already taking metformin, were reported at the virtual American Diabetes Association (ADA) 81st Scientific Sessions and published in Medscape Medical News. Researchers found the injectable drugs Lantus (glargine) and Victoza (liraglutide) outperformed the pills Amaryl (glimepiride) and … Read more

Two medications, liraglutide and insulin, were better at keeping A1C (a measurement of average blood glucose) levels less than 7% in recent GRADE study. The UNC Diabetes Care Center, lead by site principal investigator Sue Kirkman, MD, professor of medicine, in the division of endocrinology and metabolism, was one of the 37 sites to be … Read more

Magnetic Resonance in Medicine (MRM) recently highlighted research by Scott Donaldson, MD, professor of medicine, and Jennifer Goralski, MD, assistant professor of medicine and pediatrics, from the division of pulmonary and critical care medicine. Their paper “Comparison of single breath hyperpolarized 129Xe MRI with dynamic 19F MRI in cystic fibrosis lung disease” was highlighted for … Read more

Klara Klein, MD, PhD, a fellow in the division of endocrinology and metabolism, and Shetal Patel, MD, PhD, assistant professor of medicine in the division of oncology, have received physician-scientist awards to cultivate their careers as translational clinician scientists. As part of the Forward Together Strategic Plan, the UNC School of Medicine Physician Scientist Training Program (PSTP) … Read more

NC State researchers led by Ke Cheng, PhD, created a therapeutic approach that mimics the receptor that the virus binds to and then traps the virus before it infect cells. The Department of Medicine’s Jason Lobo, MD, the Kimberly H. Tsamoutales Distinguished Term Professor of Medicine, Division of Pulmonary Diseases and Critical Care Medicine, is a co-author … Read more

On May 19, the UNC Internal Medicine Residency Program held “Resident Research Day” for the 2020-2021 year. Given all of the virtual conferences over the past year, Resident Research Day was also primarily virtual, but selected residents presented their research projects during noon conference. Despite the incredibly busy clinical year, residents remained active in research … Read more

Medicine’s cardiovascular specialists care for thousands of patients every year, in clinic and in hospital, focused on one mission–exceptional heart care for the people of North Carolina while advancing the science and clinical practice of cardiovascular medicine. Following is a look at service highlights. Women’s Heart Program The UNC Women’s Heart Program provides clinic counseling … Read more

Physician researchers in the division of hospital medicine and the division of infectious diseases collaborated for the study “Frequency and yield of blood cultures for observation patients with skin and soft tissue infections,” published this month in the American Journal of Emergency Medicine. The study was designed to measure frequency and yield of blood cultures … Read more

UPDATE: This year, as a result of lower programming costs associated with the virtual format, organizers invite UNC faculty and UNC PN clinicians to attend at a reduced rate of $200 for the entire conference, or half of the daily or two-day rate. (Note, reduced rates may not be possible next year with a return … Read more

In an article titled, “Viruses, microscopy and fast radio bursts: 10 remarkable discoveries from 2020,” Nature featured an important HIV latency reversal discovery led by UNC School of Medicine researchers J. Victor Garcia, PhD, director of the International Center for the Advancement of Translational Science and professor of medicine and microbiology & immunology, and David Margolis, director … Read more