Edwing Daniel Centeno Cuadra is a research assistant at the University of North Carolina at Chapel Hill. Edwing has a master’s degree in Medical Microbiology. His career in research started in his country (Nicaragua) in 2016 in the Center of Infectious Diseases (CEI) at the National Autonomous University of Nicaragua (UNAN-Leon) at Bucardo’s laboratory by performing different molecular based diagnosis on different viral infections (Zika, dengue, chikungunya, norovirus, rotavirus, sapovirus, astrovirus), gave him the opportunity to be part of different publications in the field of virology.
He completed his Master’s in 2019, conducting research about Zika virus in the population of Leon, Nicaragua; where the main goal was to determine how long does Zika virus RNA is detectable in different body fluids (whole blood, plasma, urine and saliva) over time in different body fluids at different time points for 6 months after the development of symptoms. He found that RNA could be detected in every body fluid in different timepoints and 180 Days Post Symptom Onset (DPSO); it is important to remark that RNA was found in vaginal fluid and semen samples also for 180 DPSO, two different publications were made, helping to understand the risk of sexual transmission of this virus.
By working at UNAN he had the opportunity to be part of different research projects held in cooperation with UNC, such as: Risk Factors and Clinical Profile of Sapovirus-associated Acute Gastroenteritis in Early Childhood; Incidence of norovirus AGE in children to determine the role of Histo-blood Group Antigens (HBGAs) in susceptibility and disease severity in a genogroup- and genotype-dependent manner; Antibody response to SARS-CoV-2 infection over six months among Nicaraguan outpatients; Seroepidemiology of SARS-CoV-2 infections in an urban Nicaraguan population.
He started working at UNC at Chapel-Hill since September 2021, and he is working in the detection of antibodies against different flaviviruses to understand if having a symptomatic infection with Dengue virus could trigger the production of other antibodies against other types of flaviviruses, such as Zika virus, West-Nile virus, yellow fever virus and other Dengue virus subtypes over the first month of infection.
Bibliography LinkedIn
