In a paper published in Nature Communications, Janet Berrios, a graduate student in the Philpot lab, discovered that the loss of UBE3A decreases the release of the GABA neurotransmitter and alters reward-seeking behavior in an important neural pathway once presumed to be principally regulated by the dopamine neurotransmitter.
![image2](https://www.med.unc.edu/neuroscience/wp-content/uploads/sites/782/2018/07/philpot-and-stuber-labs-discover-a-role-for-gaba-co-release-in-the-brain2019s-reward-pathway-image2.jpeg)
![image3](https://www.med.unc.edu/neuroscience/wp-content/uploads/sites/782/2018/07/philpot-and-stuber-labs-discover-a-role-for-gaba-co-release-in-the-brain2019s-reward-pathway-image3.jpeg)
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