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Dr. Reidel’s current research activities are focused on three major public health concerns. The first is elucidating the secretome changes caused by SARS-CoV-2 on the airway surface. The other is addressing the airway effects of tobacco product use, which still is the largest preventable cause of morbidity and mortality in the United States. While it has been established that chronic cigarette smoking causes airway harm, very little is known about the effects of increasingly popular electronic nicotine delivery systems (e.g. e-cigarettes) on the airways. To study the effect of viral infections and tobacco product use on the airways Dr. Reidel mainly employs proteomic analysis of the apical airway secretion layer. This proteomic profiling provides response signatures of the airway epithelium and is helpful to elucidate airway mechanisms of innate defense and toxicity protection.


UNC AFFILIATIONS:

Marsico Lung Institute, Pathology & Lab Medicine

CLINICAL/RESEARCH INTERESTS:

Pulmonary, Toxicology, Virology