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![](https://www.med.unc.edu/oor/faculty-database/wp-content/uploads/sites/1313/2022/08/Helen-Lazear-300x286.jpg)
Flavivirus pathogenesis
-Immune mechanisms that control Zika virus and other congenital infections
-Zika virus infection in the female reproductive tract
-Host genetic determinants of neuroinvasive flavivirus pathogenesis
-Viral and host mechanisms that control flavivirus infection in the skin
-Viral determinants of Zika virus replication and pathogenesis
-No-known-vector flaviviruses
IFN-λ mediated antiviral immunity
-IFN-λ mediated immunity at the maternal-fetal interface
-IFN-λ mediated immunity in the skin
-Defining IFN-λ specific antiviral responses
Herpes simplex virus pathogenesis
-IFN-λ mediated control of HSV skin disease
-Hormonal control of HSV vaginal infection
-HSV infection and trafficking in neurons
More details at: www.lazearlab.org
UNC AFFILIATIONS: |
CLINICAL/RESEARCH INTERESTS:
Global Health, Immunology, Microbiology, Pathogenesis & Infection, Virology, Women's Health |