Laura Herring, PhD

EMAIL: laura_herring@med.unc.edu

PERSONAL WEBSITE: https://www.med.unc.edu/proteomics/

PUBLICATIONS: Publications Link

Laura Herring is the Director of the UNC Proteomics Core Facility which provides mass spectrometry-based proteomics services for the analysis of proteins from tissues, cells or other biological samples. We are available to the UNC community, as well as external customers worldwide. We are committed to educating students and researchers in the field of proteomics and will work with you from initial experimental design through publication.

We offer an array of sample preparation and instrumentation services, as well as method development and in-depth consultation to help researchers optimize their experimental design. The facility is equipped with four state-of-the-art mass spectrometry systems: Thermo QExactive HF, Thermo QExactive HF Biopharma, Thermo Fusion Lumos Tribrid and Thermo Exploris480. In addition to the mass spectrometers, we have one Thermo Ultimate3000, three Thermo Easy nLC 1200s and a 908 Devices ZipChip capillary electrophoresis device for up-front separation. We have an Agilent 1260 Infinity II HPLC for offline peptide fractionation. We offer several services including: protein identification, protein characterization, post-translational modification (PTM) profiling (for example: phosphoproteomics, acetylomics), large-scale proteomic profiling, intact mass analysis, and protein-protein interaction analyses. We can perform these services quantitatively using labeled (SILAC or TMT10plex/16plex/18plex) or label-free approaches (DDA or DIA). Comprehensive data analysis is provided through a variety of database search engines and software packages.