People with schizophrenia and their high-risk, first-degree relatives report widespread episodic memory impairments that are purportedly due, at least in part, to failures of mnemonic discrimination. Here, we examined the status of mnemonic discrimination in 36 children and adolescents (aged 11-17 years) with and without familial risk for schizophrenia by employing an object-based recognition task … Read more

Diagnosis and symptom severity in schizophrenia are associated with irregularities across neural oscillatory frequency bands, including theta, alpha, beta, and gamma. However, electroencephalographic signals consist of both periodic and aperiodic activity characterized by the (1/fX) shape in the power spectrum. In this paper, we investigated oscillatory and aperiodic activity differences between patients with schizophrenia and … Read more

In this study involving recent trauma-exposed civilians, researchers aimed to understand the complex relationship between substance use, posttraumatic stress disorder (PTSD), and depression. They utilized a large multisite dataset and tracked alcohol and cannabis use trajectories as well as PTSD and depression symptoms over a span of 3 months. The study identified three trajectory classes … Read more

Evidence was insufficient to draw conclusions about the benefits or harms of anxiety screening programs. However, clear evidence exists that treatment for anxiety is beneficial, and more limited evidence indicates that some anxiety screening instruments have acceptable accuracy to detect generalized anxiety disorder.